Xarelto for Thromboprophylaxis After Total Hip and Total Knee Arthroplasty

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Venous thromboembolism is a serious complication after total hip replacement (THR) and total knee replacement (TKR). Previous studies have reported the incidence of both asymptomatic and symptomatic deep vein thrombosis (DVT) after TKR were higher in Taiwan than other countries in Asia. Therefore, the usage of prophylactic antithrombotics should be considered. The efficacy and safety of Xarelto (Rivaroxaban) for preventing venous thromboembolism has been proved. However, there is a lack of study using prospective design to evaluate the efficacy and safety of Xarelto after THR and TKR for Taiwanese. In this study, the investigators use a randomized controlled trial design comparing the incidence of DVT, pulmonary embolism, and complications between intervention and control groups.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 20
Healthy Volunteers: f
View:

• Undergo total knee replacement or total hip replacement

Locations
Other Locations
Taiwan
Ditmanson Medical Foundation Chiayi Christian Hospital
RECRUITING
Chiayi City
Contact Information
Primary
Cheng-Ming Chou
james58.chou456@msa.hinet.net
88652765041
Time Frame
Start Date: 2023-02-01
Estimated Completion Date: 2025-12-21
Participants
Target number of participants: 178
Treatments
Experimental: Rivaroxaban
The participants are provided with Rivaroxaban 10mg
No_intervention: Control
The participants are provided without antithrombotics
Sponsors
Leads: Chiayi Christian Hospital

This content was sourced from clinicaltrials.gov